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KMID : 0665220120250030629
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Korean Journal of Food and Nutrition
2012 Volume.25 No. 3 p.629 ~ p.636
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Biotransformation of Ginsenoside by Lactobacillus brevis THK-D57 Isolated from Kimchi
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Yi Eun-Ji
Lee Jung-Min
Yi Tae-Hoo
Cho Seok-Cheol
Park Yong-Jin
Kook Moo-Chang
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Abstract
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Ginsenosides, ginseng saponin, are the principal components responsible for the pharmacological and biological activities of ginseng. In order to improve absorption and biological activities, the biotransformation of major ginsenoside to minor ginsenoside, as the more active compound, is required. In this study, we isolated Lactobacillus brevis THK-D57, which has high β-glycosidase activity, from Kimchi. The major ginsenoside Rb1 was converted to the minor ginsenoside ‘compound K’ during the fermentation of L. brevis THK-D57. The results propose that the biotransformation pathway to produce compound K is as follows: ginsenoside Rb1→ginsenoside Rd→ginsenoside F2→ginsenoside compound K.
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KEYWORD
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Lactobacillus brevis THK-D57, β-glycosidase, ginsenoside, biotransformation
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